Coronary inflammation by computed tomography pericoronary fat attenuation in MINOCA and Tako-Tsubo syndrome
Journal of the American Heart Association Sep 06, 2019
Gaibazzi N, et al. - Researchers carried out the first-ever comparison of pericoronary fat attenuation index (pFAI) using computed tomography angiography, which signifies an index related to vascular inflammation, between a group of patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) or Tako-Tsubo syndrome (TTS) and controls in this current single-center study. They found that mean pFAI displayed higher values in MINOCA/TTS when compared with controls; a finding that has been related to coronary artery inflammation. Findings revealed that the detection of angiographically invisible atherosclerotic plaques was enabled by coronary computed tomography angiography in MINOCA and TTS patients, as well as its diagnostic yield can be expanded using the simple measurement of pFAI to characterize pericoronary fat tissue.
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