Stillman AE, Gatsonis C, Lima JAC, et al. - Researchers designedd a randomized evaluation of patients with stable angina comparing utilization of noninvasive examinations trial that was a randomized, controlled, multicenter, comparative efficacy outcomes trial to evaluate if initial testing with coronary computed tomographic angiography (CCTA) is non-inferior to single-photon emission computed tomography (SPECT) myocardial perfusion imaging in directing patients with stable angina to optimal medical therapy alone or optimal medical therapy with revascularization. They randomly assigned a total of 1,050 individuals from 44 sites to CCTA (n=518) or SPECT (n=532). Mean follow‐up time was 16.2 (SD 7.9) months. No variation was found in outcomes of individuals who had stable angina and who had undergone CCTA in comparison to SPECT as the first imaging test directing them to optimal medical therapy alone or with revascularization. CCTA was found to be a better predictor of major adverse cardiovascular events and revascularization.