Hisamatsu T, et al. - Researchers prospectively compared coronary artery calcium (CAC) progression, as a marker of coronary atherosclerosis burden, between two population-based samples of 1,712 US white, black, Hispanic, and Chinese men (baseline, 2000–2002) vs 697 Japanese men in Japan (2006–2008) aged 45-74 years with no clinical cardiovascular disease. Serial computed tomography was performed with medians of 3.4 and 5.2 years between scans, respectively. They reported CAC incidence of 35.2% in white men, 26.9% in black men, 29.2% in Hispanic men, 18.9% in Chinese men, and 29.2% in Japanese men who were free of baseline CAC. According to the findings, US white men exhibited a higher CAC incidence. All the US race/ethnic groups were found to demonstrate greater increases in existing CAC vs Japanese men in Japan. Even after adjustment for differences in coronary risk factors, these differences persisted.