Orimoloye OA, Banga S, Dardari ZA, et al. - Researchers focused on the predictive value of coronary artery calcium (CAC) for atherosclerotic cardiovascular disease in Asian-Americans. In a large multicenter retrospective cohort, the CAC Consortium, a total of 1,621 asymptomatic Asian-Americans were examined. They modeled CAC in categorical (CAC = 0; CAC = 1–99; CAC = 100–399; CAC ≥ 400) and continuous [ln (CAC + 1)] forms. A mean follow-up of 12 ± 4 years was conducted. During this period, coronary heart disease (CHD) death, cardiovascular disease (CVD) death, and all-cause mortality were assessed. The study sample had a mean age of 54 (11.2) years, and 64% were men. The mean 10-year atherosclerotic cardiovascular disease risk score was estimated to be 8%. Per unit increase in In (CAC + 1) was associated with a significantly increased risk of CHD and CVD mortality. Although a relatively low-risk is seen in Asian-Americans, CHD, CVD, and all-cause mortality were strongly predicted by CAC beyond conventional risk factors.