Dinesen S, Jensen PS, Bloksgaard M, et al. - As the retinal vasculature is the only part of the microcirculation that can be directly studied by non‐invasive imaging, researchers here examined if retinal vascular oxygen saturation (rSatO₂) changes in correlation with coronary artery bypass grafting (CABG). Oxymap T1 was used to evaluate retinal metabolism; it simultaneously captures two retinal images at different wavelengths measuring the retinal arteriolar (raSatO₂) and venular (rvSatO₂) oxygen saturation. The median rSatO₂ was measured after CABG in 38 patients and in 39 healthy controls (operated for cataract) 3 to 4 days after surgery. Observations revealed positive and independent association of raSatO₂ and rvSatO₂ with CABG when patients with and without cardiovascular disease were compared. This indicates their potential utility as non‐invasive markers for coronary large artery disease.