Dorairaj S, et al. - Researchers conducted the study for describing changes in endothelial cell density and morphology following phacoemulsification combined with either excisional goniotomy with the Kahook Dual Blade (KDB-phaco) or first-generation iStent trabecular microbypass implantation (iStent-phaco). Twenty-one adult participants from one center with visually significant cataract and mild-moderate open-angle glaucoma underwent KDB-phaco or iStent-phaco in one eye and the alternate procedure in the fellow eye as part of a prospective, multicenter, randomized trial. Postoperative ECL is correlated with both KDB-phaco and iStent-phaco, with iStent-phaco producing substantially greater ECL than KDB-phaco. The clinical significance of these results is uncertain, and future research is warranted to more robustly describe the long-term effects of glaucoma surgical procedures on ECD and corneal health, with and without permanent implants, and to establish evidence-based guidelines for pre-and post-operative corneal health assessment in eyes undergoing glaucoma surgery.