Cord blood anti-parasite IL-10 as risk marker for compromised vaccine immunogenicity in early childhood
The Journal of Infectious Diseases Feb 03, 2018
Malhotra I, et al. - Researchers here investigated the relation of maternal prenatal infections and newborns’ anti-parasite cytokine profiles with IgG responses to standard vaccination during infancy. As per observations, antenatal sensitization to schistosomiasis or filariasis, and related production of anti-parasite IL-10 at birth were found to be associated with reduced anti-vaccine IgG levels in infancy, with possibly impaired protection.
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