Louthrenoo W, et al. - In order to evaluate susceptible human leukocyte antigen (HLA) alleles and their correlations with clinical features in Thai individuals with Behçet's disease (BD), researchers determined 18 HLA-A and 36 HLA-B alleles in 42 Thai BD individuals and 99 healthy controls (HCs) by reverse line blot assay, and reconfirmed by MICRO SSP assay. Compared with HCs, the BD individuals had significantly higher allele frequency (AF) of HLA-B*51. In BD individuals, HLA-B*51:01 was not seen with gastrointestinal involvement or arthritis. Moreover, they observed that the AF of HLA-B*51:01 was significantly higher in HLA-A*26:01 non-carrier BD patients without arthritis. For Thai BD individuals, HLA-B*51:01 was a susceptible allele, and correlated with posterior uveitis and visual impairment. The data showed that HLA-A*26:01 was another susceptible allele in HLA-B*51X non-carrier patients. Further study is needed to determine the protective impact of HLA-B*51:01 on arthritis.