Sorin V, Faermann R, Yagil Y, et al. - This retrospective study was performed to assess the role of contrast-enhanced spectral mammography (CESM) for imaging of palpable breast abnormalities and compare it to the current routine imaging workup. Between 2012 and 2019, 138 women were recruited with palpable breast masses who underwent diagnostic CESM and ultrasound. They estimated and compared diagnostic parameters for low-energy images, CESM, and targeted ultrasound. The investigation was conducted at the lesion level. The outcomes of this study indicated that CESM could be beneficial for the evaluation of palpable breast abnormalities, potentially reducing the number of unnecessary benign biopsies performed.