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Continuous positive airway pressure vs standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): A multicentre, randomised controlled trial

The Lancet Respiratory Medicine Apr 09, 2020

Wimms AJ, Kelly JL, Turnbull CD, et al. - Whether continuous positive airway pressure affords a clinically effective management option for patients with mild obstructive sleep apnoea was determined in the MERGE trial, a multicentre, parallel, randomised controlled trial. Participants were patients (≥18 years to ≤ 80 years) suffering from mild obstructive sleep apnoea (apnoea-hypopnoea index ≥ 5 to ≤ 15 events per h using either AASM 2007 or AASM 2012 scoring criteria) recruited from 11 UK sleep centres. The participants were allocated (1:1) to either 3 months of continuous positive airway pressure plus standard care (sleep counselling), or standard care alone. Findings revealed that quality of life of patients with mild obstructive sleep apnoea got improved after 3 months of treatment with continuous positive airway pressure. The necessity for health-care professionals and providers to consider management for patients with mild obstructive sleep apnoea was highlighted.

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