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Continuous magnesium infusion to prevent atrial fibrillation after cardiac surgery: A sequential matched case-controlled pilot study

Journal of Cardiothoracic and Vascular Anesthesia Jun 04, 2020

Osawa EA, Cutuli SL, Cioccari L, et al. - Researchers undertook this sequential, matched, case-controlled pilot study to investigate if atrial fibrillation (AF) occurrence post-cardiac surgery might be prevented by administering a bolus of magnesium followed by continuous intravenous infusion. This study included matched cohort with 99 patients prior to and intervention cohort with 99 consecutive patients following the introduction of a continuous magnesium infusion protocol. The magnesium infusion protocol comprised a 10 mmol loading dose of magnesium sulphate followed by a continuous infusion of 3 mmol/h over a maximum span of 96 hours or until ICU discharge. According to the findings, among cardiac surgery patients, a reduced incidence of postoperative AF was reported in relation to the magnesium delivery strategy.

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