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Continuous hemofiltration improves the prognosis of bacterial sepsis complicated by liver dysfunction in children

BMC Pediatrics Aug 16, 2018

Cui Y, et al. - In patients with bacterial sepsis complicated by liver dysfunction, researchers assessed the impacts of continuous hemofiltration via retrospectively analyzing the medical records of 27 cases of bacterial sepsis with liver dysfunction admitted to pediatric intensive care unit (PICU) of Shanghai Children’s Hospital between January 2013 and December 2016. It was observed that continuous hemofiltration significantly decreases the serum levels of total bilirubin (TBIL), direct bilirubin (DBIL), total bile acids (TBA), lactate (Lac), ammonia, tumor necrosis factor-α (TNF-α), interleukin − 6 (IL-6), and improves 28-day mortality of patients with bacterial sepsis complicated by liver dysfunction.
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