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Continuous glucose monitoring to evaluate glycaemic abnormalities in cystic fibrosis

Archives of Diseases in Childhood Feb 02, 2018

Pu MZMH, et al. - In this study, researchers determined the glycaemic profile of patients with cystic fibrosis using a continuous glucose monitoring system (CGMS). In addition, they ascertained the associations of glycaemic abnormalities with sex, age, pubertal stage, CFTR gene mutations, nutritional status, lung function, oral glucose tolerance test, glycated haemoglobin concentrations, fasting insulin concentrations, C peptide concentrations and exocrine pancreatic function. Observations revealed that among patients with cystic fibrosis and ‘normal’ oral glucose tolerance test results, CGMS could detect hyperglycaemia. For distinguishing between patients who did and did not exhibit these excursions, their clinical and laboratory characteristics were not valuable.
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