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Continual measurement of arterial dP/dtmax enables minimally invasive monitoring of left ventricular contractility in patients with acute heart failure

Critical Care Dec 08, 2019

Ostadal P, et al. - Researchers focused on the link between arterial dP/dtmax and left ventricular (LV) dP/dtmax evaluated using echocardiography in patients with acute heart failure. For this study, they recruited 48 patients (mean age 70.4 years [65% male]) with acute heart failure needing intensive care and hemodynamic monitoring. They used arterial line pressure waveform analysis to continually monitor hemodynamic variables, including arterial dP/dtmax. They evaluated LV dP/dtmax via continuous-wave Doppler analysis of mitral regurgitation flow. According to the findings, monitoring of LV contractility may be done by continuous calculation of arterial dP/dtmax in patients with acute heart failure needing intensive care with an arterial line, this may be used particularly in those with higher systemic vascular resistance (SVR), lower cardiac output (CO), and lower stroke volume (SV), such as in patients with cardiogenic shock. In the subgroups with higher CO, higher SV, and lower SVR, findings revealed only a weak or no significant correlation.
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