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Consecutive operative procedures in patients with Marfan syndrome up to 28 years after initial aortic root surgery

European Journal of Cardio-Thoracic Surgery Aug 17, 2018

Puluca N, et al. - As a surgical intervention for aortic root dilatation and frequent consecutive operations on the remaining thoracic aorta or the heart valves are required among most of the patients (75%) with Marfan syndrome, researchers delineated the spectrum of such procedures. They retrospectively analyzed data from all patients with Marfan syndrome undergoing aortic root surgery at their centre between 1988 and 2016. In the setting of Marfan syndrome, subsequent procedures after the initial surgery were most often performed on the remaining native aorta, followed by the aortic and mitral valves. Findings revealed that the necessity for additional operative procedures continued to remain high, even decades after the initial surgeries are undertaken. This emphasizes the significance of long-term patient monitoring at specialized centres.
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