Ladomenou F, et al. - Researchers conducted this retrospective observational study to examine the effect of vaccination on bacterial meningitis over a period of 27 years in a well-defined children's population on the island of Crete, Greece. This was a study of all compulsory bacterial meningitis notifications from 1991-2017 in patients aged 1 month to 14 years. The present data indicated that there were 245 patients with proven (n = 227) or suspected (n = 18) bacterial meningitis and eight deaths, resulting in a case fatality rate of 3.3%. It was noted that the mean annual incidence rate per 100,000 children was 4.9 for Neisseria meningitidis, 2.2 for Streptococcus pneumoniae and 0.4 for Haemophilus influenzae type b (Hib). The authors discovered that cases of bacterial meningitis decreased in children following the introduction of the Meningitis C and PCV13 vaccines in Greece. Hib had already vanished and major reeductions have been observed in meningitis C and Streptococcus pneumoniae.