Hutchcraft ML, et al. - In this investigation involving 115 patients, researchers assessed the additive value of a cone biopsy's pathological characteristics to identify patients with high-risk tumors for which adjuvant therapy may be indicated. For this analysis, they retrospectively identified patients with early stage cervical cancer undergoing a conization followed by radical hysterectomy from 1995 to 2016. From patient medical records, clinical and pathologic data were abstracted. According to results, conization lymphovascular space invasion was linked to high-risk final pathology. Conization additive pathology and hysterectomy specimen did not have a significant impact on risk stratification in women with early stage cervical cancer, affecting only 4.3% of patients. In 60% of cases and high-risk criteria in 37% of cases, however, the presence of lymphovascular space invasion (LVSI) in the conization was related to intermediate risk criteria. Since patients with intermediate/high-risk criteria would meet adjuvant therapy recommendations, LVSI evaluation in conization specimens may influence the selection of primary therapy for women with cervical cancer.