Fareed MM, et al. - In this analysis of all non-metastatic gallbladder cancer (GBC) and cholangiocarcinoma (CCA) patients at a single institution who had definitive resection from 1992–2016, researchers compared outcomes, including overall survival (OS), locoregional failure and distant failure, between those who received neoadjuvant therapy (chemotherapy and/or radiation) vs those who did not. They used the Kaplan-Meier method and log rank tests to assess OS. To assess time to recurrence, they used Cox proportional hazard models. Findings highlighted that CCA patients treated with adjuvant therapy tended to have better survival, relative to GBC patients. The seeming variance in recurrence patterns among the two was probably due to treatment modality used, patient selection, or unmeasured factors.