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Computed tomographic coronary angiography in risk stratification prior to non-cardiac surgery: A systematic review and meta-analysis

Heart Apr 30, 2019

Koshy AN, et al. - Researchers assessed the utility of CT coronary angiography (CTA) and coronary artery calcium (CAC) score in preoperative risk prognostication before non-cardiac surgery, by analyzing evidence from 11 relevant studies published up to June 2018 in MEDLINE, PubMed and EMBASE databases. A total of 3480 patients with 252 (7.2%) major adverse cardiovascular events (MACE) occurrences were included. The risk for perioperative MACE increased with the severity and extent of coronary artery disease on CTA. The greatest risk was observed in multivessel disease. Findings also revealed an association between increasing CAC score and higher perioperative MACE. CTA demonstrated a comparable ‘rule-out’ capability than other non-invasive imaging modalities. In addition, CTA offers a viable alternative for risk stratification of such patients.
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