Jakob T, et al. - Researchers aimed to overview current studies on the use of component-resolved diagnostics in the field of Hymenoptera venom allergy (HVA) and discuss its benefits and limitations. They observed that component-resolved diagnostics allows a better understanding of the complexity of sensitization and cross-reactivities in HVA. Moreover, the enhanced resolution and precision may allow identification of biomarkers, which can be used for risk stratification in VIT. According to individual sensitization profiles, knowledge about the molecular composition of different therapeutic preparations may enable the selection of appropriate preparations for venom immunotherapy, an approach consistent with the goals of personalized medicine.