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Complications, costs, and quality outcomes of patients undergoing cervical deformity surgery with intraoperative BMP use

Spine Nov 02, 2020

Varshneya K, Wadhwa H, Pendharkar AV, et al. - An epidemiological study using national administrative data from the MarketScan database was designed to distinguish the impact of bone morphogenetic protein (BMP) on postoperative outcomes in patients undergoing adult cervical deformity (ACD) surgery. The MarketScan database was queried to distinguish individuals who had undergone ACD surgery from 2007 to 2015. Researchers included a sum of 13,549 patients who had undergone primary ACD surgery, of which 1,155 (8.5%) had intraoperative BMP use. It was shown that in ACD surgery, intraoperative BMP use has benefits for fusion integrity but is correlated with elevated postoperative complication rate. In ACD surgery, spine surgeons should weigh these advantages and drawbacks to distinguish optimal candidates for BMP use.

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