Lo Vecchio A, et al. - From January 2016 to August 2017, the Italian Society for Paediatric Infectious Diseases conducted a retrospective study in children hospitalized for measles to examine the risk factors for severe results defined by the presence of long-lasting sequelae, the need for intensive care or death. Nineteen hospitals registered 249 children (median age 14.5 months): 207 (83%) children developed a complication and 3 (1%) children died. In children with B3 genotype, neutropaenia was more commonly reported compared to other genotypes. Data reported that pancreatitis and encephalitis were linked to severe results in multivariable analysis and C reactive protein (CRP), the increase of which predicted severe results. It was noted that CRP values >2 mg/dL were related to a higher risk of complications or severe outcome. Findings suggested that the risk of severe results in measles is independent of age and underlying conditions, but is associated with the development of organ complications and can be predicted by the CRP value.