Bajraktari G, et al. - Researchers compared the efficacies of complete revascularization (CR) vs revascularization of only the infarct-related artery (IRA) during primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD). According to the analysis of 10 randomized clinical trials (RCTs) with 3291 patients, CR attenuated the risk of major adverse cardiac events, repeat revascularization, and cardiac death for patients with STEMI and MVD undergoing primary PCI. However, when compared to the isolated culprit lesion-only treatment, no significant difference was observed in the risk for all-cause mortality and PCI-related complications. The cardiac mortality and safety benefit of CR in stable STEMI was supported.