Yzet C, Diouf M, Le Mouel JP, et al. - Given that mucosal healing (MH) was correlated with good outcomes of patients with Crohn disease (CD), researchers conducted this retrospective study to evaluate long-term outcomes of patients with CD according to different levels of MH. The sample consisted of 84 individuals with CD and MH who received biologic therapy (80% with infliximab) from 2008 through 2015 at two university hospitals in France and contrasted outcomes of patients with CD endoscopic index scores (CDEISs) of 0 vs CDEISs greater than 0 but less than 4. Twenty-seven patients had treatment failure and three patients had an intestinal resection after a median follow-up time of 4.8 years. Findings suggested an association of complete endoscopic healing (CDEIS = 0) with better long-term outcomes compared with partial endoscopic healing (CDEIS = 1–4) in patients with CD, as well as fewer surgeries and hospitalizations and overall reduced risk of treatment failure.