Gagnat AA, et al. - Given that low-dose computed tomography (LDCT) has been recommended in guidelines on screening programs for lung cancer on the basis of the National Lung Cancer Screening Trial (NLST) and COPD-LUCSS has been proposed by De Torres et al to improve selection criteria, researchers assessed and compared the two with respect to their discriminating value in a community-based cohort of COPD patients. Participants included 422 ever-smokers with COPD from the GenKOLS study. Cancer Registry of Norway was also used. The links between the scores and lung cancer were assessed using Cox regression and logistic regression. Discriminating values were calculated using Harrell's C and area under the curve (AUC). Increased risk of lung cancer was reported in relation to both the COPD-LUCSS and the NLST criteria. Poor discriminating abilities of these models were demonstrated by the AUC and Harrell's C values in the studied cohort. No significant superiority of COPD-LUCSS over NLST criteria was established.