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Comparison of the effects of target-controlled infusion of propofol and sevoflurane as maintenance of anesthesia on hemodynamic profile in kidney transplantation

Anesthesiology Research and Practice Dec 07, 2019

Aditianingsih D, et al. - Researchers performed this single-blinded prospective study to determine how intraoperative hemodynamic profile in kidney transplant patients were altered by the use of either target-controlled infusion (TCI) propofol or sevoflurane. This study included 46 kidney transplant recipients. The participants were randomized to receive TCI propofol or sevoflurane as anesthetics maintenance. At baseline prior to induction, after intubation, first surgical incision, every 15 minutes following the first incision, reperfusion, and 15 minutes following reperfusion, measurements of hemodynamic parameters such as mean arterial pressure, cardiac index (CI), stroke volume index (SVI), and systemic vascular resistance index (SVRI) were obtained and evaluated. Findings revealed similar intraoperative hemodynamic profile between the TCI propofol and sevoflurane group during kidney transplant surgery. Higher CI and SVI but significantly lower SVRI were seen in the TCI propofol group vs the sevoflurane group. The two groups showed no significant difference in terms of the incidence of postanesthesia agitation, postoperative outcome, and complication.
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