Di Serafino L, et al. - The efficacy of dual-axis rotational coronary angiography (DARCA) to prevent acute kidney injury (AKI), relative to conventional coronary angiography (CCA), was assessed herein. DARCA vs CCA significantly attenuated both X-Ray Exposition and the amount of contrast medium usage, thereby reducing the occurrence of AKI.

• Researchers enrolled consecutive patients undergoing coronary angiography to DARCA (n=80) or CCA (n=80).
• They excluded patients presenting with ST-segment elevation myocardial infarction (STEMI) or previously undergone to coronary artery bypass graft.

• In terms of both clinical and procedural characteristics, the 2 groups were homogeneous.
• In DARCA group vs CCA, significantly lower total XR-time and total contrast medium amount were reported (XR-time: (3.2min (1.8-7.0) vs 5.1min (2.6-9.9), p=0.002; Contrast medium amount: (40ml (31-116) vs 80ml (50-150), p<0.001).
• Furthermore, occurrence of AKI in the CCA group was more often, as compared with DARCA (16 (20%) vs 4 (5%), p=0.007).
• Moreover, researchers observed that in patients presenting with ACS or undergoing PCI, AKI more often occurred in CCA as compared with DARCA (ACS patients, 6 (29%) vs 2 (6%), p=0.04 and, PCI patients, 11 (33%) vs 0 (0%), p<0.001).
• They also noted that among patients with high pre-test probability (PTP) of coronary artery disease (CAD), AKI more often occurred in CCA group as compared with DARCA (11 (55%) vs 2 (6%), p<0.001).