Comparison of survival benefits of nephron-sparing intervention or active surveillance for patients with localized renal masses: A systematic review and meta-analysis
BMC Urology Aug 11, 2019
Guo RQ, et al. - A systematic literature search that defined nephron-sparing intervention (NSI), partial nephrectomy and thermal ablation were involved in a systematic review and meta-analysis by the researchers in order to contrast the outcomes of survival, including cancer-specific survival (CSS), overall survival (OS), and cardiovascular-specific survival (CVSS), in individuals with renal masses who underwent NSI or active surveillance (AS). Seven studies including 5,809 individuals were involved. The results comparing NSI with AS were CSS with HR = 0.64, 95%CI = 0.46–0.89, OS with HR = 0.46, 95%CI = 0.39–0.53, and CVSS with HR = 0.37, 95%CI = 0.24–0.57. Hence, in comparison with AS for individuals with renal masses, NSI was related to better OS, CSS, and CVSS.
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