Noaman S, et al. - Researchers examined patients presenting with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI) to assess the correlation of proximal and nonproximal location of culprit coronary lesions with clinical outcomes. They used the Victorian Cardiac Outcomes Registry and identified 3,283 patients with STEMI. These patients were analyzed and outcomes were compared in those with proximal lesion location vs patients with nonproximal location. They observed greater hemodynamic instability and higher-risk features among patients with proximal lesion location; however, proximal lesions vs nonproximal lesions did not show an independent relation to worse clinical outcomes.