Urata CN, Mariottoni EB, Jammal AA, et al. - In this prospective cohort involving 43 glaucoma individuals (43 eyes), researchers evaluated short-term and long-term variability on standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT) in glaucoma. To test the hypothesis of equality between short-term and long-term variability, Wilcoxon signed-rank test was conducted. According to findings, long-term variability on SD-OCT and SAP was higher than short-term variability. Since current event-based algorithms for detecting glaucoma progression on SAP and SD-OCT rely on short-term variability information to create their normative databases, these algorithms may underestimate long-term variability and may, therefore, overestimate progression over time.