Song JW, et al. - This study investigated the impact of adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) polymorphisms on the prophylactic efficacy of ramosetron versus palonosetron against postoperative nausea and vomiting (PONV) in patients who received intravenous patient-controlled analgesia after spinal surgery. Possibly, ramosetron has a greater potential for attenuating PONV severity than palonosetron, particularly in patients with ABCB1 3435TT or 2677TT genotype.