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Comparison of quantitative ultrasound of calcaneus and dual energy X-ray absorptiometry in measuring bone density and predicting fractures in patients with diabetic polyneuropathy: A prospective cohort study

Diabetes Research and Clinical Practice Sep 26, 2021

Ugarph-Morawski A, Sääf M, Brismar K, et al. - Because quantitative ultrasound (QUS) of calcaneus predicted fractures in diabetic patients with numerous comorbidities, it seems reasonable to investigate QUS of the calcaneus as a fracture risk predictor in primary care.

  • Sixty-two hospital foot clinic patients with type 1 or type 2 diabetes and complications were followed (1995-2015; 610 person-years).

  • Clinical examinations and QUS of the calcaneus were done on all participants at the time of inclusion, as well as dual-energy X-ray absorptiometry (DXA) of the spine and femoral neck on a subgroup (n = 34).

  • Bone density (QUS of calcaneus) was found to be associated to hip bone density (DXA).

  • All fractures (30/62 patients; 48% ) and hip fractures (6/62 patients; 10%) were more common in patients than in the general population.

  • Twelve people (19%) had foot fractures.

  • DXA did not predict hip, lower leg, or foot fractures; QUS of the calcaneus did.

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