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Comparison of pregnancy outcomes following preimplantation genetic testing for aneuploidy using a matched propensity score design

Human Reproduction Sep 03, 2020

Haviland MJ, Murphy LA, Modest AM, et al. - Researchers examined whether the likelihood of live birth increases among women undergoing autologous IVF who have fertilized embryos in correlation with undergoing preimplantation genetic testing for aneuploidy (PGT-A). In this retrospective cohort study, they analysed data from 8,227 women who underwent autologous IVF treatment, had their first oocyte retrieval from January 1, 2011 through October 31, 2017 and had fertilized embryos from this retrieval. Overall, women with fertilized embryos who underwent PGT-A were significantly less likely to have an embryo transfer but were more likely to have a cycle that resulted in a clinical pregnancy and live birth relative to women who did not use PGT-A. Outcomes thereby suggest correlation of undergoing PGT-A with a greater probability of live birth among women 35 years old and older who are undergoing IVF.

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