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Comparison of platelet function guided vs unguided treatment with P2Y12-inhibitors in patients with acute myocardial infarction (From the Hungarian Myocardial Infarction Registry)

The American Journal of Cardiology Feb 21, 2018

Komocsi A, et al. - Researchers, herein, focused on the clinical benefits of selecting P2Y12-inhibitors based on platelet function testing (PFT). It was shown that PFT-guided treatment with a high rate of switch-over to prasugrel was associated with a lower risk for mortality among acute myocardial infarction (AMI) patients. Furthermore, prasugrel was identified as a predictor of lower mortality in patients with high platelet reactivity on clopidogrel, but not in the overall cohort of AMI.
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