Baeriswyl M, et al. - Researchers theorized that increased block duration would be attained after ultrasound-guided popliteal sciatic nerve block in type-2 diabetic patients suffering from diabetic peripheral neuropathy, vs patients without neuropathy. To test this theory, they prospectively included diabetic patients with neuropathy and non-diabetic control patients, scheduled for fore-foot surgery. Primary as well as secondary outcomes were analyzed using an accelerated failure time regression model. They found that patients with diabetic peripheral neuropathy vs those without neuropathy showed reduced time to onset of sensory blockade, with increased time to first opioid request following an ultrasound-guided popliteal sciatic nerve block.