Zhang T, et al. - The clinical outcomes of using a cortical screw (CS) for lumbar interbody fusion were assessed by comparison with conventional pedicle screw (PS) fixation by the researchers via 12 studies with a total of 835 patients. Relative to operating time, intraoperative blood loss, length of stay, the incidence of complications, adjacent segmental disease (ASD) incidence, and Oswestry Disability Index (ODI), the use of CS fixation for lumbar interbody fusion was better than conventional PS fixation. Nonetheless, no statistically notable variations in the back and leg pain visual analog scale (VAS), Japanese Orthopaedic Association (JOA) scale, and intervertebral fusion rate between the CS fixation group and the PS fixation group were noted. Thus, in lumbar interbody fusion, it was indicated that both CS and conventional PS could lead to good postoperative outcomes. In the back and leg pain VAS, JOA scale, and intervertebral fusion rate, no important variations were discovered. Nonetheless, CS fixation is better than PS fixation in terms of operating time, intraoperative blood loss, length of stay, the incidence of complications, ASD incidence, and ODI.