Wang J, et al. - Researchers analyzed 274 consecutive patients with nonmetastatic soft tissue sarcoma (STS) of extremities and trunk treated with postoperative intensity-modulated radiation therapy (IMRT) (n = 187) and two-dimensional radiotherapy (2D-RT) (n = 87) to assess the survival outcomes and late toxicities of postoperative IMRT vs 2D-RT in these patients. Outcomes suggest that postoperative IMRT results in better local recurrence-free survival, distant metastasis-free survival, disease-free survival (DFS), and overall survival and less late toxicities in these patients when compared with conventional techniques. Hence it should be offered as a preferred treatment.