Comparison of macular pigment optical density in glaucoma patients and healthy subjects - A prospective diagnostic study
Clinical Ophthalmology Apr 06, 2020
Bruns Y, et al. - Researchers conducted this prospective diagnostic case-control study to explore the connection macular pigment optical density (MPOD) and glaucoma. Participants in the study were 43 patients with an established glaucoma diagnosis [mean age 70 (range 34– 84)] and 43 healthy controls [mean age 62 (range 30– 87)]. The median of the visual field mean defect was 5.1 db and the mean RNFL-thickness global was 65.9 μm in the glaucoma group. Findings revealed that there was no proof for lower MPOD levels and no increased glare disability in the glaucoma patients. However, at 1.02° retinal eccentricity, there seems to be a strong association between age and MPOD. In order to further investigate the relationship between glare reported in patients with glaucoma and glare disability associated with lower MPOD levels, further studies are needed, including both a detailed study of glare quality and glare quantification and accurate analysis of MPOD levels in glaucoma patients.
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