Kaewkumnert S, Phithaksinsuk K, Changpoo C, et al. - In this randomized, triple-blind, split-mouth clinical trial, researchers compared the impact of intraosseous dexamethasone injection and submucosal dexamethasone injection on postoperative sequelae following mandibular third molar surgery. According to the side (right and left), 54 mandibular third molars (27 patients) were subdivided; intraosseous injection of dexamethasone (4 mg) was randomly assigned to one side and submucosal injection to the other. Findings revealed that there was no significant difference between the two injection techniques in pain or swelling. Nonetheless, on postoperative day 3, there was a significant difference in trismus, with a better result being shown by submucosal injection. All dexamethasone injection methods have been successful in controlling pain and swelling following third-molar mandibular surgery, but the submucosal injection was superior for trismus control.