Kim M, Hwang JY, Choo KS, et al. - Experts assessed the impact of iso-osmolar contrast media (IOCM) at various tube voltages on image quality for abdominal CT in pediatric patients. Contrast enhancement was significantly greater in the low osmolar contrast media group (LOCM), relative to the objective measurement. In the subjective analysis, only CT using 120 kVp exhibited significantly stronger enhancement in the LOCM group, and sensitivity to distinguish the IOCM was 80.6%. For correctly distinguishing IOCM, overall sensitivity and specificity were 57.1%, and 56.9%, respectively. Thus, for performing pediatric abdominopelvic CT with a low tube voltage protocol, the application of IOCM was observed to be feasible. Nevertheless, objective measurements of contrast enhancement were significantly lower in the IOCM group, subjective contrast enhancement and image quality evaluations were not statistically distinctive among groups.