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Comparison of fatigue and fatigability correlates in korean breast cancer survivors and differences in associations with anxiety, depression, sleep disturbance, and endocrine symptoms: a randomized controlled trial

BMC Cancer Jul 29, 2021

Jang MK, Han J, Kim SH, et al. - This study attempted to explore the effects of a 15-month intervention on fatigue and fatigability in breast cancer survivors (BCS); investigated the fatigue-fatigability relationship; and assessed the impacts of fatigue and fatigability on anxiety, depression, sleep disturbance, and endocrine symptoms. Researchers assessed the survey responses of 40 BCS using the chi-square test and multiple regression analysis at the completion of the intervention. They further used Korean versions of the Revised Piper Fatigue Scale and Pittsburgh Fatigability Scale to assess fatigue and fatigability, respectively. It was shown that fatigue and fatigability demonstrated different associations with cancer-related symptoms after the exercise intervention. Further evaluations of fatigability in intervention studies will allow measurement of the spectrum of patients’ abilities to overcome fatigue at various physical activity levels while capturing different aspects of cancer-related symptoms.

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