Xu L, et al. - Researchers intended to establish a reliable threshold to accurately quantify epicardial adipose tissue (EAT) volume from contrast-enhanced (CE) datasets by analyzing EAT volume on paired non-contrast (NC) and CE datasets from 25 patients. To equalize two EAT volume estimates, appropriate Hounsfield cutpoints were derived. They applied a threshold correction to (-190HU, -30HU) based on mean differences in radiodensity between NC and CE images (ΔEATrd = CE radiodensity - NC radiodensity). In 21 additional patients with paired computed tomography (CT) datasets, findings on EAT threshold were validated. EAT volume estimates generated from contrast-enhanced CT scans using a corrected threshold of -190HU, -3HU were found to be in excellent agreement with EAT volume from non-contrast CT scans using a standard threshold of -190HU, -30HU.