Vu KN, et al. - In this retrospective observational study, researchers compared respiratory motion artifact and diagnostic image quality between end-inspiration and end-expiration breath-holding techniques on unenhanced and contrast-enhanced axial T1-weighted MRI of the liver. The study sample consisted of 50 consecutive subjects undergoing axial T1-weighted liver MRI, with unenhanced images acquired with both end-inspiration and end-expiration breath-holding techniques, as well as contrast-enhanced images acquired for 47 of the subjects with either the end-inspiration or the end-expiration breath-holding technique. There was a significant improvement in motion scores for sequences acquired in end-expiration compared to sequences acquired in end-inspiration for unenhanced sequences, contrast-enhanced sequences, and subtraction images. Compared to the end-inspiration technique, the end-expiration breath-holding technique results in significant decreases in respiratory motion artifacts on unenhanced and contrast-enhanced T1-weighted liver MRI.