Comparison of drug administration logistics between prothrombin complex concentrates and plasma in the Emergency Department
The American Journal of Emergency Medicine Apr 02, 2018
Alarfaj SJ, et al. - Researchers aimed at comparing the time from order to start of administration between 3-factor prothrombin complex concentrate (PCC3), 4-factor (PCC4), and fresh frozen plasma (FFP) in the Emergency Department (ED). They also evaluated the effect of an ED pharmacist on time to administration of PCCs. For emergency bleeding, PCC is used as an alternative to FFP. They recognized that compared to FFP, time from order to administration is faster with PCC. The time from order to administration of PCC reduced with ED pharmacist involvement.
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