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Comparison of donor cornea endothelial cell density determined by eye banks and by a central reading center in the cornea preservation time study

Cornea Mar 10, 2019

Benetz BA, et al. - In the Cornea Image Analysis Reading Center (CIARC), researchers examined the agreement between eye banks (EBs) and a reading center on endothelial cell density (ECD) determinations. They recorded mean preoperative ECD ie, 15 cells/mm2 higher by the EBs as compared by CIARC with 95% limits of agreement of (−644, 675 cells/mm2). They noted that EBs-determined preoperative ECD was within 10% of the CIARC-determined ECD for 886 (69%) image sets, with 236 above by >10% and 164 lower by >10%. Overall, they suggested comparable mean ECD by the EBs and CIARC. Although, significant variability between determinations for particular corneas was also considered.
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