Comparison of disk diffusion and agar dilution methods for gentamicin susceptibility testing of Neisseria gonorrhoeae
Diagnostic Microbiology and Infectious Disease Apr 07, 2018
Gianecini R, et al. - Researchers analyzed the suitability and reliability of disk diffusion to monitor the susceptibility of Neisseria gonorrhoeae to gentamicin. In this work, they noted no N. gonorrhoeae isolates with resistance to gentamicin. When compared with the agar dilution method, the disk diffusion had strong correlation. Despite a high percentage of minor discrepancies, reduction in the error rate was observed adjusting the breakpoint. This suggests that in clinical laboratories, the disk diffusion can serve as a screening method to detect the gentamicin susceptibility of N. gonorrhoeae.
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