Comparison of chitinase-3-like protein 1, aspartate aminotransferase-to-platelet ratio index, and fibrosis-4 index with shear-wave elastography
European Journal of Gastroenterology & Hepatology Feb 09, 2019
Mushtaq S, et al. - Researchers conducted the study to analyze the comparison of chitinase-3-like protein 1 (CHI3L1), aspartate aminotransferase-to-platelet ratio index and fibrosis-4 (Fib-4) index with shear-wave elastography (SWE), a routine method for pre-assessment of liver fibrosis. Among 150 recruited patients with chronic hepatitis who had serum analysis and SWE, researchers evaluated CHI3L1 or YKL-40 level, aspartate aminotransferase-to-platelet ratio index, and Fib-4 index. The study findings suggested that CHI3L1 could be used as a preliminary tool to evaluate mild/absent fibrosis from significant fibrosis and cirrhosis.
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