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Comparison of carotid plaque characteristics between men and women using magnetic resonance vessel wall imaging: A Chinese atherosclerosis risk evaluation study

Journal of Magnetic Resonance Imaging Mar 05, 2021

Zhang L, Zhu L, Lu M, et al. - Researchers undertook this cross‐sectional analysis to compare carotid atherosclerotic plaque characteristics between males and females in a Chinese population employing magnetic resonance imaging. Participants were 567 patients (mean age: 61.5 ± 10.1 years; 404 men) who suffered a recent stroke or transient ischemia attack and had atherosclerotic plaque in at least one carotid artery. In symptomatic arteries, significantly greater lumen area (LA), wall area (WA), and total vessel area (TVA); higher mean wall thickness (MWT); as well as higher prevalence of lipid‐rich necrotic core (LRNC) and intraplaque hemorrhage (IPH) were observed in males vs females. In asymptomatic arteries, significantly greater LA, WA, and TVA; higher MWT; higher prevalence of LRNC, IPH, and fibrous cap rupture; as well as higher %LRNC area were detected in males vs females. In this Chinese population, males vs females were found to have similar plaque burden but more vulnerable atherosclerotic plaques in both symptomatic as well as asymptomatic carotid arteries.

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