Rodriguez-Ruiz A, et al. - In a fully-crossed multi-reader multi-case study, researchers compared breast cancer detection and depiction between planar synthetic mammography (SM) and rotating synthetic mammography (RM) generated from digital breast tomosynthesis (DBT). Three radiologists retrospectively reviewed 190 cases (27 malignant, 31 benign, 132 normal), once with SM alone and once with RM alone; the DBT stack of slices was not reviewed. The present data indicated that radiologists achieve similar cancer detection with RM as with SM, and they significantly preferred the display of all types of lesions in RM over SM. It was noted that the average reading time per case was higher for RM vs SM.