Comparison between the histopathological and immunophenotypical features of hypopigmented and non‐hypopigmented mycosis fungoides: A retrospective study
Journal of Cutaneous Pathology Sep 27, 2020
Jayasinghe DR, et al. - In this cross‐sectional, retrospective study, researchers sought to objectively compare the clinicopathological features of hypopigmented mycosis fungoides (HMF) with non‐HMF lesions in order to characterize salient features of HMF. For this investigation, they analyzed biopsy specimens of 87 patients with MF. HMF and non‐HMF groups have been contratsted utilizing clinical data, immunophenotypic features and scores given for six histopathological characteristics: dermal infiltrate, basilar and superficially‐extending epidermotropism, Pautrier microabscesses and dermal and epidermotropic lymphocytic atypia. Compared with non‐HMF, HMF presents at a lower age and earlier stage with a female predominance. The diagnosis of HMF requires association with clinical features and careful assessment of epidermotropic cells due to milder dermal infiltrates, less dermal atypia, and Pautrier microabscesses.
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries